Postdoctoral Scientist at MRC Laboratory of Molecular Biology

The MRC Laboratory of Molecular Biology (LMB) is a research institute within UK Research and Innovation (UKRI). UKRI is an entity^{that brings together nine partnersto create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.}

We are looking for a postdoctoral scientist to join the group of Sjors Scheres to work on cryo-EM structure determination of amyloid filaments. Specifically, to explore lab-based model systems (using purified recombinant proteins or cells) that will allow the formation of amyloid filaments with the same structures as those observed in neurodegenerative disease. Once identified, these systems will be exploited to gain mechanistic insights into the molecular processes that underlie the structural specificity of filament formation in disease.

You will become part of our bubbly, multi-disciplinary team that operates in close collaboration with the group of Michel Goedert, who is also at the MRC-LMB. You will become an expert in experimental cryo-EM structure determination, and you will benefit from further interactions with the wider scientific community at the MRC-LMB. You are highly motivated to work on amyloids and have a PhD in a relevant subject or be due to complete within 6 months. Previous experience with either amyloids or cryo-EM will be an advantage.

Group web site: Scheres lab (cam.ac.uk)   

The successful applicant will be awarded a Career Development Fellowship/ Postdoctoral Training Scheme position on a fixed term until 31 March 2026.  This is a training and development position for a Postdoctoral Scientist who has recently completed their doctoral studies, is moving into a new research discipline or has limited experience of key transferable skills. The MRC LMB has excellent scientific core facilities and training opportunities.

Working for UKRI provides a whole host of benefits including a defined benefit pension scheme and excellent holiday entitlement (40 ½ days including bank holidays and privilege days). You will also have access to employee shopping and travel discounts, on-site sport and social facilities, as well as a salary sacrifice scheme for cycle to work.

To apply and access full details of the vacancy please visit our job board via the ‘Apply’ button above.

If you are unable to apply online please contact us at recruit@mrc-lmb.cam.ac.uk. 

Final appointments will be subject to a pre-employment screening.

The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.