[ad_1] Location: Hammersmith Campus (East Acton) Job Summary We have an exciting opportunity to appoint a talented and ambitious post
[ad_1]
Location: Hammersmith Campus (East Acton)
Job Summary
We have an exciting opportunity to appoint a talented and ambitious post-doctoral research associate to join our multidisciplinary 3-year collaborative project, funded by the Medical Research Council entitled: “An integrative transethnic approach to identify novel functional genes in Parkinson’s disease using in silico and in vivo experiments”.
This innovative project is a collaboration between centres at Imperial College and University College London. It will apply state-of-the-art analytical methods to integrate multi-ancestry genomic data to understand how genetic loci for Parkinson’s disease (PD) confer risk of disease using computational analyses. The work will focus upon how PD loci may confer risk of disease by altering the expression of neighbouring (cis-genes) and distal genes (trans-genes). The project offers a unique opportunity in that a selection of identified genes will then be functionally validated using fly models of PD.
We anticipate that results from this study will help us to systematically investigate the underlying genetic architecture for PD. The project will provide tools to enable a more comprehensive view of genetic risk and of the causal genes and biological mechanisms underlying common diseases that will be relevant to all populations, irrespective of their genetic ancestry, and will offer new opportunities for clinical translational studies.
The successful candidate will join an inter-disciplinary team of geneticists and clinicians with a wide range of expertise in genetics, functional genomics, statistics, and epidemiology at Imperial College (Dr Toby Andrew, Genetics and Genomics) and at UCL. Suitable candidates will have a strong background in genetics, computational biology, bioinformatics or statistics, with a PhD in a relevant subject and will have experience in the analysis of genomic data and strong computational skills in a Linux environment.
Duties and Responsibilities
- To take initiatives in the planning of research
- To conduct genetic and genomic data analyses
- To always ensure the validity and reliability of data
- To maintain accurate and complete records of all findings
- To present findings to colleagues and at conferences
- To submit publications to refereed journals
Essential Requirements
- Research Associate: Hold a PhD in genetics, molecular biology, computational biology or a related discipline
- Research Assistant: Near completion of a PhD in genetics, molecular biology, computational biology or a related discipline
- Strong experience in genomic data analysis
- Practical experience within a research environment and / or publication in relevant and refereed journals
- Experience of coding bioinformatics pipelines
Further Information
Previous applicants need not apply.
This is a full time and fixed term post for 1 year. You will be based at the Hammersmith Campus (East Acton).
Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £38,194 – £41,388 per annum.
How to apply:
As part of your application, please also include:
- A brief personal statement of no more than 1,000 words, explaining your interest in the project, your experience and why you are applying for the job.
- Your CV
- The names and addresses of at least two academic referees
Selected candidates will be interviewed at UCL and can request an informal visit to the Hammersmith campus before interview.
Please contact Toby Andrew for further details: t.andrew@imperial.ac.uk
Closing date: 21 June 2023
[ad_2]
Source link
COMMENTS