[ad_1] The role We have an exciting opportunity to join the molecular epidemiology group of the MRC Integrative Epidemiology Unit at
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The role
We have an exciting opportunity to join the molecular epidemiology group of the MRC Integrative Epidemiology Unit at the University of Bristol as a Senior Research Associate. The initial project will analyse molecular data generated by the Biomarkers in Atopic Dermatitis and Psoriasis (BIOMAP, https://www.biomap-imi.eu/) project with the aim of determining causal relationships between intermediate omics traits and Atopic Dermatitis and Psoriasis subtypes to identify potential target mechanisms.
The position is available on a full time or part time basis, with funding initially available for 10 months. Further funding may become available to extend the position.
What will you be doing?
You will perform statistical analysis of DNA methylation and gene expression data from blood and skin samples, to link molecular signatures to Atopic Dermatitis and Psoriasis subtypes. You will use Mendelian Randomization to determine which associations have causal evidence. You will be presenting these findings in scientific publications and conference presentations and your research will contribute to improve intervention discovery and inform health practice for Atopic Dermatitis and Psoriasis.
You should apply if
You have a strong background (PhD or postdoctoral research) in molecular epidemiology or bioinformatics, experience using statistical programming languages (such as R) and preferably some experience of working with large-scale molecular datasets. You have experience of applied statistical analysis and preferably have understanding of epigenome wide association studies and Mendelian randomization methods.
You will be joining a large and diverse world-class research team at a leading institution. The molecular epidemiology group of the MRC IEU is a dynamic group with a rapidly growing portfolio of grant-funded projects. You will be encouraged to contribute your own ideas, take responsibility for discrete projects and you will be supported in achieving your career development goals.
The MRC IEU research environment is truly interdisciplinary and highly collaborative. The team have expertise spanning methodological, applied and translational research across diverse areas such as cardiovascular disease, cancer, perinatal health and mental health.
This role is based in Oakfield House, Clifton, Bristol and there is an operational requirement to work on-site for a proportion of the working week. If desired and with suitable arrangements in place, it is possible to fulfil part of the role remotely.
Bristol is a diverse and progressive city with good transport links and beautiful locations for recreation on the doorstep.
Additional information
Contract type: Fixed term initially for 10 months from the start date
Work pattern: Full-time / 1FTE (Part-time considered)
Grade: Grade J/ Pathway Two
School/Unit: Bristol Medical School
Shift pattern: 35h per week (Part-time considered)
This advert will close at 23:59 GMT on 30/07/2023
For informal queries please contact: Dr Josine Min (josine.min@bristol.ac.uk) or Dr Lavinia Paternoster (l.paternoster@bristol.ac.uk)
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The University of Bristol aims to be a place where everyone feels able to be themselves and do their best in an inclusive working environment where all colleagues can thrive and reach their full potential. We want to attract, develop, and retain individuals with different experiences, backgrounds and perspectives – particularly people of colour, LGBT+ and disabled people – because diversity of people and ideas remains integral to our excellence as a global civic institution.
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