Influence of Polyphenol Supplementation on Nitric Oxide Biomarkers, Cardiovascular and Mitochondrial Function, and Exercise Capacity in Older Adults at Loughborough University

Is the project University funded or self-funded?: University funded

Funding eligibility (please select one): Directly funded project (students worldwide)

Subject area. Please tick as many as apply: Science

PhD project title: Influence of polyphenol supplementation on nitric oxide biomarkers, cardiovascular and mitochondrial function, and exercise capacity in older adults

Is the project UKRI funded?: No

Is the project industry funded?: Yes

Has the contract with the industrial partner been completed? yes

Closing date of advert: 9th August 2023

Start date: October 2023

Full-time/part-time availability: Full-time 3 years

Who is eligible to apply?: Both UK and International

Name of primary supervisor/CDT lead: Dr Stephen Bailey

Primary supervisor email address: s.bailey2@lboro.ac.uk

Link to supervisor’s online staff profile page: https://www.lboro.ac.uk/schools/sport-exercise-health-sciences/people/stephen-bailey/

Project detail:

This project will assess the efficacy of polyphenol supplementation to alter nitric oxide and redox biomarkers; muscle respiration, morphology and molecular responses; cardiovascular function; and exercise capacity in healthy older adults. This project will be supervised by an interdisciplinary team to provide training in various laboratory techniques including exercise testing, flow mediated dilation, ozone-based chemiluminescence, high resolution respirometry, immunohistochemistry and western blotting.

Entry requirements:

• An upper second class degree (or equivalent) in appropriate subject such as Sport and Exercise Science; Physiology; Nutrition/Dietetics; Biochemistry; Biosciences; or Molecular Biology
• MSc in appropriate subject such as Sport and Exercise Science; Physiology; Nutrition/Dietetics; Biochemistry; Biosciences; or Molecular Biology
• Experience or a working knowledge in the assessment of cardiovascular function such as flow mediated dilation
• Experience or a working knowledge in the assessment blood biomarkers
• Experience or a working knowledge in the assessment of skeletal muscle respiration, morphology and molecular responses using techniques such as respirometry, immunohistochemistry and western blotting
• Experience in conducting human nutrition and exercise trials
• Excellent oral and written communication skills
• Ability to critically appraise scientific methodology and data
• Ability to work well individually and as a member of a larger research team

English language requirements:

Applicants must meet the minimum English language requirements. Further details are available on the International website (http://www.lboro.ac.uk/international/applicants/english/).

Funding information:

The PhD studentship is for 3 years and due to commence on 1st October 2023. The studentship provides a tax free stipend of £18,622 per annum plus tuition fees for 3 years at either UK or international student rates.

How to apply:

All applications should be made online. Under programme name, select School of Sport, Exercise and Health Sciences. Please quote the advertised reference number: SSEHS/SB in your application.

To avoid delays in processing your application, please ensure that you submit the minimum supporting documents. Specifically, please provide a CV and a personal statement outlining your motives for applying and how you feel your skills and experiences meet the requirements of this position.

Project search terms:

cardiology, cell biology, complementary medicine, molecular biology, nutrition, physiology, sport & exercise science – other

Email Address SSEHS: pgr-ssehs@lboro.ac.uk

Email address: s.bailey2@lboro.ac.uk

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