[ad_1] We have an opportunity for a Research Associate to join the School of Cancer Sciences. The successful candidate will contribute
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We have an opportunity for a Research Associate to join the School of Cancer Sciences.
The successful candidate will contribute to/make a leading contribution to a project “Targeting metabolic vulnerability in chronic myeloid leukaemia by serine restriction”, working with Professor Vignir Helgason’s Lab at the Wolfson Wohl Cancer Research Centre, Glasgow.
The Helgason Lab has demonstrated that inhibition of folate metabolism (also referred to as one-carbon metabolism) reduces de novo purine synthesis and drives differentiation of CML cells through mTORC1 mediated purine sensing. We also have strong preliminary data suggesting that CML cells may depend on serine (major one-carbon donor) for optimal proliferation and survival. The aim of this project is to uncover the importance of serine catabolism for CML stem cells and propose that dietary amino acid restriction can be tested therapeutically in future clinical trials in stem cells driven leukaemias. The successful candidates will be expected to address the hypothesis that one-carbon metabolism is a targetable metabolic vulnerability in CML and help manage and direct this exciting and challenging project as opportunities allow.
Candidates should have extensive lab-based experience along with specialist theoretical and practical knowledge in a research related field (Cancer Metabolism | Leukaemia).
Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £32,332 – £36,024 per annum.
For further information, please contact Professor Vignir Helgason Vignir.Helgason@glasgow.ac.uk
This post is full time and has funding for up to 3 years.
Apply online at: my.corehr.com/pls/uogrecruit/erq_jobspec_version_4.jobspec?p_id=125828
We believe that we can only reach our full potential through the talents of all. Equality, diversity and inclusion are at the heart of our values. Applications are particularly welcome from across our communities and in particular people from the Black, Asian and Minority Ethnic (BAME) community, and other protected characteristics who are under-represented within the University. Read more on how the University promotes and embeds all aspects of equality and diversity within our community www.gla.ac.uk/myglasgow/humanresources/equalitydiversity
We endorse the principles of Athena Swan www.gla.ac.uk/myglasgow/humanresources/equalitydiversity/athenaswan and hold bronze, silver and gold awards across the University.
We are investing in our organisation, and we will invest in you too.
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