[ad_1] The Sheffield Gene Therapy Innovation and Manufacturing Centre (GTIMC) is one of three cutting-edge hubs in the UK dedicated to
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The Sheffield Gene Therapy Innovation and Manufacturing Centre (GTIMC) is one of three cutting-edge hubs in the UK dedicated to advancing the clinical development of new genetic treatments options for millions of patients with life-threatening diseases.
Gene therapy is a promising treatment option for a number of diseases that currently have no other cures including inherited disorders.
The Sheffield Hub, which is the first in the north of England, is part of an £18 million network created by LifeArc and the Medical Research Council (MRC), with support from the Biotechnology and Biological Sciences Research Council (BBSRC)
The GTIMC is located on the site of the University of Sheffield’s Innovation District close to the centres of Sheffield and Rotherham and within easy reach of major transportation corridors and regional shopping and entertainment complexes.
The centre includes a cutting-edge GMP (good manufacturing practice) facility that will support gene therapy projects emerging from universities across the UK.
The facility will utilise highly efficient processes to manufacture clinical grade adeno-associated viruses (AAV) and provide all the necessary quality assurance and regulatory certification for human trials at NHS hospital sites.
You will lead the implementation of the GMP production strategy and introduce and maintain key policies and procedures to improve the robustness and efficiency of all manufacturing operations. You will identify improvements to the processes and systems to allow efficient manufacturing of clinical vectors for life changing gene therapies for patients. Managing a team of 15 with a view to grow the GTIMC team to around 35 over the next 3 years. The Head of GMP will help establish and develop the GMP regulation and will be responsible for the day-to-day management, operation, scheduling, and administration of the GMP clean rooms.
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